TY  - GEN
AU  - Yamada,Akihiro
AU  - Maeda,Kazuya
AU  - Kamiyama,Emi
AU  - Sugiyama,Daisuke
AU  - Kondo,Tsunenori
AU  - Shiroyanagi,Yoshiyuki
AU  - Nakazawa,Hayakazu
AU  - Okano,Teruo
AU  - Adachi,Masashi
AU  - Schuetz,John D
AU  - Adachi,Yasuhisa
AU  - Hu,Zhuohan
AU  - Kusuhara,Hiroyuki
AU  - Sugiyama,Yuichi
TI  - Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor
SN  - 0090-9556
PY  - 2008///0103
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - metabolism
KW  - ATP Binding Cassette Transporter, Subfamily G, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - Adenosine Triphosphate
KW  - Angiotensin II Type 1 Receptor Blockers
KW  - Animals
KW  - Cell Line
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Estrone
KW  - analogs & derivatives
KW  - Female
KW  - Hepatocytes
KW  - drug effects
KW  - Humans
KW  - Imidazoles
KW  - In Vitro Techniques
KW  - Kidney
KW  - Kinetics
KW  - Liver
KW  - Liver-Specific Organic Anion Transporter 1
KW  - Membrane Transport Proteins
KW  - Mice
KW  - Mice, Knockout
KW  - Multidrug Resistance-Associated Protein 2
KW  - Multidrug Resistance-Associated Proteins
KW  - deficiency
KW  - Neoplasm Proteins
KW  - Olmesartan Medoxomil
KW  - Organic Anion Transporters
KW  - Organic Anion Transporters, Sodium-Independent
KW  - Penicillin G
KW  - pharmacology
KW  - Probenecid
KW  - Prodrugs
KW  - Protein Binding
KW  - Protein Isoforms
KW  - Sincalide
KW  - Solute Carrier Organic Anion Transporter Family Member 1B3
KW  - Tetrazoles
KW  - Transfection
KW  - p-Aminohippuric Acid
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/dmd.107.017459
ER  -