TY - GEN AU - Hlobilkova,A AU - Ehrmann,J AU - Sedlakova,E AU - Krejci,V AU - Knizetova,P AU - Fiuraskova,M AU - Kala,M AU - Kalita,O AU - Kolar,Z TI - Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression? SN - 0028-2685 PY - 2007///1023 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Astrocytoma KW - metabolism KW - Cell Cycle KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Disease Progression KW - ErbB Receptors KW - Female KW - Gene Expression Regulation, Neoplastic KW - Glial Fibrillary Acidic Protein KW - Humans KW - Male KW - Middle Aged KW - Mutation KW - genetics KW - Oligodendroglioma KW - PTEN Phosphohydrolase KW - Phosphatidylinositol 3-Kinases KW - Phosphorylation KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-mdm2 KW - Signal Transduction KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -