Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression? [electronic resource]
- Neoplasma 2007
- 334-41 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0028-2685
Adolescent Adult Aged Aged, 80 and over Astrocytoma--metabolism Cell Cycle Cyclin-Dependent Kinase Inhibitor p21--metabolism Disease Progression ErbB Receptors--metabolism Female Gene Expression Regulation, Neoplastic Glial Fibrillary Acidic Protein--metabolism Humans Male Middle Aged Mutation--genetics Oligodendroglioma--metabolism PTEN Phosphohydrolase--metabolism Phosphatidylinositol 3-Kinases--metabolism Phosphorylation Proto-Oncogene Proteins c-akt--metabolism Proto-Oncogene Proteins c-mdm2--metabolism Signal Transduction Tumor Suppressor Protein p53--genetics