TY - GEN AU - Roecker,Anthony J AU - Coleman,Paul J AU - Mercer,Swati P AU - Schreier,John D AU - Buser,Carolyn A AU - Walsh,Eileen S AU - Hamilton,Kelly AU - Lobell,Robert B AU - Tao,Weikang AU - Diehl,Ronald E AU - South,Vicki J AU - Davide,Joseph P AU - Kohl,Nancy E AU - Yan,Youwei AU - Kuo,Lawrence C AU - Li,Chunze AU - Fernandez-Metzler,Carmen AU - Mahan,Elizabeth A AU - Prueksaritanont,Thomayant AU - Hartman,George D TI - Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP SN - 0960-894X PY - 2007///1212 KW - Binding Sites KW - Crystallography, X-Ray KW - Drug Design KW - Humans KW - Hydrogen KW - chemistry KW - Kinesins KW - antagonists & inhibitors KW - Mitosis KW - drug effects KW - Models, Molecular KW - Molecular Structure KW - Pyrazoles KW - chemical synthesis KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2007.07.074 ER -