TY  - GEN
AU  - Josien,Hubert
AU  - Bara,Thomas
AU  - Rajagopalan,Murali
AU  - Asberom,Theodros
AU  - Clader,John W
AU  - Favreau,Leonard
AU  - Greenlee,William J
AU  - Hyde,Lynn A
AU  - Nomeir,Amin A
AU  - Parker,Eric M
AU  - Pissarnitski,Dmitri A
AU  - Song,Lixin
AU  - Wong,Gwendolyn T
AU  - Zhang,Lili
AU  - Zhang,Qi
AU  - Zhao,Zhiqiang
TI  - Small conformationally restricted piperidine N-arylsulfonamides as orally active gamma-secretase inhibitors
SN  - 0960-894X
PY  - 2007///1127
KW  - Administration, Oral
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Amyloid beta-Peptides
KW  - biosynthesis
KW  - Animals
KW  - Area Under Curve
KW  - Cytochrome P-450 Enzyme System
KW  - metabolism
KW  - Drug Design
KW  - Magnetic Resonance Spectroscopy
KW  - Mice
KW  - Molecular Conformation
KW  - Molecular Weight
KW  - Oxidoreductases
KW  - Piperidines
KW  - chemical synthesis
KW  - Sulfonamides
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2007.08.013
ER  -