Josien, Hubert <br/><br/>
Small conformationally restricted piperidine N-arylsulfonamides as orally active gamma-secretase inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Oct 2007 
 - 5330-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2007.08.013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Amyloid beta-Peptides--biosynthesis<br/>Animals<br/>Area Under Curve<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Drug Design<br/>Magnetic Resonance Spectroscopy<br/>Mice<br/>Molecular Conformation<br/>Molecular Weight<br/>Oxidoreductases--metabolism<br/>Piperidines--chemical synthesis<br/>Sulfonamides--chemical synthesis