TY  - GEN
AU  - Ling,Yan
AU  - Li,Zhu-Hong
AU  - Miranda,Kildare
AU  - Oldfield,Eric
AU  - Moreno,Silvia N J
TI  - The farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates
SN  - 0021-9258
PY  - 2007///1212
KW  - Alternative Splicing
KW  - drug effects
KW  - Amino Acid Motifs
KW  - Amino Acid Sequence
KW  - Animals
KW  - Baculoviridae
KW  - Bone Density Conservation Agents
KW  - pharmacology
KW  - Catalysis
KW  - Cloning, Molecular
KW  - Diphosphates
KW  - metabolism
KW  - Diphosphonates
KW  - Diterpenes
KW  - Dolichols
KW  - biosynthesis
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - Escherichia coli
KW  - enzymology
KW  - Farnesyltranstransferase
KW  - antagonists & inhibitors
KW  - Gene Expression
KW  - Gene Expression Regulation, Enzymologic
KW  - Geranyltranstransferase
KW  - Isoenzymes
KW  - Molecular Sequence Data
KW  - Polyisoprenyl Phosphates
KW  - Protein Prenylation
KW  - Protozoan Proteins
KW  - Quantitative Trait Loci
KW  - physiology
KW  - Recombinant Proteins
KW  - Sesquiterpenes
KW  - Sterols
KW  - Toxoplasma
KW  - Toxoplasmosis
KW  - diet therapy
KW  - Ubiquinone
KW  - analogs & derivatives
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M703178200
ER  -