Ling, Yan <br/><br/>
The farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates.  [electronic resource] 

 -  The Journal of biological chemistry  Oct 2007 
 - 30804-16 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M703178200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alternative Splicing--drug effects<br/>Amino Acid Motifs<br/>Amino Acid Sequence<br/>Animals<br/>Baculoviridae<br/>Bone Density Conservation Agents--pharmacology<br/>Catalysis<br/>Cloning, Molecular<br/>Diphosphates--metabolism<br/>Diphosphonates--pharmacology<br/>Diterpenes--metabolism<br/>Dolichols--biosynthesis<br/>Drug Design<br/>Enzyme Inhibitors--pharmacology<br/>Escherichia coli--enzymology<br/>Farnesyltranstransferase--antagonists & inhibitors<br/>Gene Expression<br/>Gene Expression Regulation, Enzymologic--drug effects<br/>Geranyltranstransferase--antagonists & inhibitors<br/>Isoenzymes--antagonists & inhibitors<br/>Molecular Sequence Data<br/>Polyisoprenyl Phosphates--biosynthesis<br/>Protein Prenylation--drug effects<br/>Protozoan Proteins--antagonists & inhibitors<br/>Quantitative Trait Loci--physiology<br/>Recombinant Proteins--antagonists & inhibitors<br/>Sesquiterpenes<br/>Sterols--biosynthesis<br/>Toxoplasma--enzymology<br/>Toxoplasmosis--diet therapy<br/>Ubiquinone--analogs & derivatives