Hill, Courtney E

The L84F polymorphism in the O6-Methylguanine-DNA-Methyltransferase (MGMT) gene is associated with increased hypoxanthine phosphoribosyltransferase (HPRT) mutant frequency in lymphocytes of tobacco smokers. [electronic resource] - Pharmacogenetics and genomics Sep 2007 - 743-53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1744-6872

10.1097/FPC.0b013e3281111eb1 doi


Adult
Age Factors
Aged
Alkylating Agents--toxicity
Base Sequence
DNA Modification Methylases--genetics
DNA Primers--genetics
DNA Repair--genetics
DNA Repair Enzymes--genetics
Female
Genotype
Humans
Hypoxanthine Phosphoribosyltransferase--genetics
Lymphocytes--drug effects
Male
Middle Aged
Mutation
Pharmacogenetics
Polymorphism, Single Nucleotide
Smoking--genetics
Tumor Suppressor Proteins--genetics