TY  - GEN
AU  - Miknyoczki,Sheila
AU  - Chang,Hong
AU  - Grobelny,Jennifer
AU  - Pritchard,Sonya
AU  - Worrell,Candace
AU  - McGann,Natalie
AU  - Ator,Mark
AU  - Husten,Jean
AU  - Deibold,James
AU  - Hudkins,Robert
AU  - Zulli,Allison
AU  - Parchment,Ralph
AU  - Ruggeri,Bruce
TI  - The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity
SN  - 1535-7163
PY  - 2007///1015
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Carbazoles
KW  - Cell Death
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Comet Assay
KW  - DNA Damage
KW  - DNA Repair
KW  - Dacarbazine
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Enzyme Inhibitors
KW  - G2 Phase
KW  - Humans
KW  - Irinotecan
KW  - Mice
KW  - Phthalimides
KW  - Poly Adenosine Diphosphate Ribose
KW  - metabolism
KW  - Poly(ADP-ribose) Polymerase Inhibitors
KW  - Rats
KW  - Temozolomide
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/1535-7163.MCT-07-0062
ER  -