Miknyoczki, Sheila <br/><br/>
The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity.  [electronic resource] 

 -  Molecular cancer therapeutics  Aug 2007 
 - 2290-302 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1535-7163 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-07-0062  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Camptothecin--analogs & derivatives<br/>Carbazoles--pharmacology<br/>Cell Death--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Comet Assay<br/>DNA Damage<br/>DNA Repair--drug effects<br/>Dacarbazine--analogs & derivatives<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Synergism<br/>Enzyme Inhibitors--pharmacology<br/>G2 Phase--drug effects<br/>Humans<br/>Irinotecan<br/>Mice<br/>Phthalimides--pharmacology<br/>Poly Adenosine Diphosphate Ribose--metabolism<br/>Poly(ADP-ribose) Polymerase Inhibitors<br/>Rats<br/>Temozolomide<br/>Xenograft Model Antitumor Assays