TY - GEN AU - Ghalit,Nourdin AU - Reichwein,John F AU - Hilbers,Hans W AU - Breukink,Eefjan AU - Rijkers,Dirk T S AU - Liskamp,Rob M J TI - Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics SN - 1439-4227 PY - 2007///1029 KW - Alkanes KW - chemical synthesis KW - Alkenes KW - Anti-Bacterial Agents KW - Catalysis KW - Chromatography, High Pressure Liquid KW - Chromatography, Thin Layer KW - Computers, Molecular KW - Cyclization KW - Drug Design KW - Fluoresceins KW - chemistry KW - Models, Molecular KW - Molecular Mimicry KW - Nisin KW - Peptide Fragments KW - Phosphatidylcholines KW - metabolism KW - Polyisoprenyl Phosphate Oligosaccharides KW - Stereoisomerism KW - Unilamellar Liposomes KW - Uridine Diphosphate N-Acetylmuramic Acid KW - analogs & derivatives N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/cbic.200700244 ER -