TY - GEN AU - Lee-Kirsch,Min Ae AU - Gong,Maolian AU - Chowdhury,Dipanjan AU - Senenko,Lydia AU - Engel,Kerstin AU - Lee,Young-Ae AU - de Silva,Udesh AU - Bailey,Suzanna L AU - Witte,Torsten AU - Vyse,Timothy J AU - Kere,Juha AU - Pfeiffer,Christiane AU - Harvey,Scott AU - Wong,Andrew AU - Koskenmies,Sari AU - Hummel,Oliver AU - Rohde,Klaus AU - Schmidt,Reinhold E AU - Dominiczak,Anna F AU - Gahr,Manfred AU - Hollis,Thomas AU - Perrino,Fred W AU - Lieberman,Judy AU - Hübner,Norbert TI - Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus SN - 1061-4036 PY - 2007///1127 KW - 3' Untranslated Regions KW - genetics KW - Endosomes KW - metabolism KW - Exodeoxyribonucleases KW - chemistry KW - Frameshift Mutation KW - Gene Frequency KW - Genetic Predisposition to Disease KW - Genotype KW - Green Fluorescent Proteins KW - HeLa Cells KW - Humans KW - Lupus Erythematosus, Cutaneous KW - enzymology KW - Mutation KW - Mutation, Missense KW - Phosphoproteins KW - Protein Structure, Tertiary KW - Recombinant Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ng2091 ER -