Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. [electronic resource]
- Nature genetics Sep 2007
- 1065-7 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1061-4036
10.1038/ng2091 doi
3' Untranslated Regions--genetics Endosomes--metabolism Exodeoxyribonucleases--chemistry Frameshift Mutation Gene Frequency Genetic Predisposition to Disease Genotype Green Fluorescent Proteins--genetics HeLa Cells Humans Lupus Erythematosus, Cutaneous--enzymology Mutation Mutation, Missense Phosphoproteins--chemistry Protein Structure, Tertiary Recombinant Proteins--genetics