TY - GEN AU - Martinez Molina,Daniel AU - Wetterholm,Anders AU - Kohl,Andreas AU - McCarthy,Andrew A AU - Niegowski,Damian AU - Ohlson,Eva AU - Hammarberg,Tove AU - Eshaghi,Said AU - Haeggström,Jesper Z AU - Nordlund,Pär TI - Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase SN - 1476-4687 PY - 2007///0905 KW - Apoenzymes KW - chemistry KW - Binding Sites KW - Catalysis KW - Crystallography, X-Ray KW - Glutathione KW - Glutathione Transferase KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Inflammation Mediators KW - metabolism KW - Lipid Metabolism KW - Models, Molecular KW - Protein Binding KW - Protein Conformation KW - Structure-Activity Relationship KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nature06009 ER -