TY - GEN AU - Liao,Guanghong AU - Yao,Yueqin AU - Liu,Jihua AU - Yu,Zhang AU - Cheung,Simon AU - Xie,Ang AU - Liang,Xiaoli AU - Bi,Xiaoning TI - Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain SN - 0002-9440 PY - 2007///1206 KW - Animals KW - Autophagy KW - Brain KW - cytology KW - Cathepsin B KW - metabolism KW - Cathepsin D KW - Child KW - Cholesterol KW - Filipin KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Lysosomes KW - Mice KW - Mice, Inbred BALB C KW - Mice, Knockout KW - Microtubule-Associated Proteins KW - Niemann-Pick C1 Protein KW - Niemann-Pick Diseases KW - Proteins KW - genetics KW - Purkinje Cells N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2353/ajpath.2007.070052 ER -