Buehler, Paul W

Effects of endogenous ascorbate on oxidation, oxygenation, and toxicokinetics of cell-free modified hemoglobin after exchange transfusion in rat and guinea pig. [electronic resource] - The Journal of pharmacology and experimental therapeutics Oct 2007 - 49-60 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3565

10.1124/jpet.107.126409 doi


Animals
Ascorbic Acid--blood
Blood Pressure--drug effects
Blood Substitutes--pharmacokinetics
Cattle
Cell-Free System
Drug Stability
Guinea Pigs
Heart Rate--drug effects
Hemoglobins--pharmacokinetics
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Kidney--drug effects
Male
Myocardium--pathology
Oxidation-Reduction
Oxygen--blood
Plasma Exchange
Rats
Rats, Sprague-Dawley