Souza, Danielle G <br/><br/>
Effects of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in a model of intestinal reperfusion injury in mice.  [electronic resource] 

 -  European journal of pharmacology  Sep 2007 
 - 72-80 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0014-2999 
<br/><br/><label>Standard No.: </label>10.1016/j.ejphar.2007.05.058  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ADAM Proteins--antagonists & inhibitors<br/>ADAM17 Protein<br/>Animals<br/>Capillary Permeability--drug effects<br/>Chemokines--blood<br/>Cytokines--blood<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Enzyme-Linked Immunosorbent Assay<br/>Hydroxamic Acids--administration & dosage<br/>Interleukin-10--blood<br/>Intestinal Mucosa--metabolism<br/>Intestines--blood supply<br/>Lung--drug effects<br/>Male<br/>Matrix Metalloproteinase Inhibitors<br/>Matrix Metalloproteinases--metabolism<br/>Mice<br/>Mice, Inbred C57BL<br/>Oligopeptides--administration & dosage<br/>Reperfusion Injury--metabolism<br/>Survival Rate<br/>Tumor Necrosis Factor-alpha--blood