Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of bile acid synthesis. [electronic resource]
- Journal of lipid research Dec 1990
- 2149-58 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
0022-2275
Acyl Coenzyme A--antagonists & inhibitors Animals Bile Acids and Salts--biosynthesis Cholesterol--metabolism Cholesterol 7-alpha-Hydroxylase--metabolism Dehydrocholesterols--metabolism Down-Regulation Kinetics Liver--enzymology Male Mevalonic Acid--analogs & derivatives Rats Rats, Inbred Strains trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride--pharmacology