Pandak, W M

Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of bile acid synthesis. [electronic resource] - Journal of lipid research Dec 1990 - 2149-58 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

0022-2275


Acyl Coenzyme A--antagonists & inhibitors
Animals
Bile Acids and Salts--biosynthesis
Cholesterol--metabolism
Cholesterol 7-alpha-Hydroxylase--metabolism
Dehydrocholesterols--metabolism
Down-Regulation
Kinetics
Liver--enzymology
Male
Mevalonic Acid--analogs & derivatives
Rats
Rats, Inbred Strains
trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride--pharmacology