TY  - GEN
AU  - Morales,Pablo R
AU  - Dillehay,Dirck L
AU  - Moody,Steven J
AU  - Pallas,David C
AU  - Pruett,Sarah
AU  - Allgood,Jeremy C
AU  - Symolon,Holly
AU  - Merrill,Alfred H
TI  - Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation
SN  - 0148-0545
PY  - 2007///0830
KW  - Acylation
KW  - Adenocarcinoma
KW  - drug therapy
KW  - Administration, Oral
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - BALB 3T3 Cells
KW  - Biotransformation
KW  - Body Weight
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Chemical and Drug Induced Liver Injury
KW  - Chromatography, High Pressure Liquid
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Hematocrit
KW  - Humans
KW  - Kidney Diseases
KW  - chemically induced
KW  - Liver
KW  - Liver Diseases
KW  - pathology
KW  - Male
KW  - Methylation
KW  - Mice
KW  - Mice, Transgenic
KW  - Prostatic Intraepithelial Neoplasia
KW  - Prostatic Neoplasms
KW  - Spectrometry, Mass, Electrospray Ionization
KW  - Sphingosine
KW  - Tissue Distribution
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1080/01480540701375018
ER  -