Morales, Pablo R <br/><br/>
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.  [electronic resource] 

 -  Drug and chemical toxicology  2007 
 - 197-216 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>0148-0545 
<br/><br/><label>Standard No.: </label>10.1080/01480540701375018  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acylation<br/>Adenocarcinoma--drug therapy<br/>Administration, Oral<br/>Animals<br/>Antineoplastic Agents--administration & dosage<br/>BALB 3T3 Cells<br/>Biotransformation<br/>Body Weight--drug effects<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Chemical and Drug Induced Liver Injury<br/>Chromatography, High Pressure Liquid<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Hematocrit<br/>Humans<br/>Kidney Diseases--chemically induced<br/>Liver--drug effects<br/>Liver Diseases--pathology<br/>Male<br/>Methylation<br/>Mice<br/>Mice, Transgenic<br/>Prostatic Intraepithelial Neoplasia--drug therapy<br/>Prostatic Neoplasms--drug therapy<br/>Spectrometry, Mass, Electrospray Ionization<br/>Sphingosine--administration & dosage<br/>Tissue Distribution