TY  - GEN
AU  - Bruno,Olga
AU  - Brullo,Chiara
AU  - Bondavalli,Francesco
AU  - Schenone,Silvia
AU  - Ranise,Angelo
AU  - Arduino,Nicoletta
AU  - Bertolotto,Maria B
AU  - Montecucco,Fabrizio
AU  - Ottonello,Luciano
AU  - Dallegri,Franco
AU  - Tognolini,Massimiliano
AU  - Ballabeni,Vigilio
AU  - Bertoni,Simona
AU  - Barocelli,Elisabetta
TI  - Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis
SN  - 0022-2623
PY  - 2007///1015
KW  - Actins
KW  - antagonists & inhibitors
KW  - Adult
KW  - Animals
KW  - Anti-Inflammatory Agents
KW  - chemical synthesis
KW  - Chemotaxis, Leukocyte
KW  - Humans
KW  - Interleukin-8
KW  - pharmacology
KW  - Male
KW  - Mice
KW  - N-Formylmethionine Leucyl-Phenylalanine
KW  - Neutrophils
KW  - drug effects
KW  - Peritoneal Cavity
KW  - cytology
KW  - Peritonitis
KW  - pathology
KW  - Phenylurea Compounds
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-akt
KW  - metabolism
KW  - Pseudopodia
KW  - Pyrazoles
KW  - Receptors, Interleukin-8A
KW  - Receptors, Interleukin-8B
KW  - Structure-Activity Relationship
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm0704402
ER  -