Bruno, Olga <br/><br/>
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.  [electronic resource] 

 -  Journal of medicinal chemistry  Jul 2007 
 - 3618-26 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0704402  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Actins--antagonists & inhibitors<br/>Adult<br/>Animals<br/>Anti-Inflammatory Agents--chemical synthesis<br/>Chemotaxis, Leukocyte<br/>Humans<br/>Interleukin-8--pharmacology<br/>Male<br/>Mice<br/>N-Formylmethionine Leucyl-Phenylalanine--pharmacology<br/>Neutrophils--drug effects<br/>Peritoneal Cavity--cytology<br/>Peritonitis--pathology<br/>Phenylurea Compounds--chemical synthesis<br/>Phosphorylation<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Pseudopodia--drug effects<br/>Pyrazoles--chemical synthesis<br/>Receptors, Interleukin-8A--metabolism<br/>Receptors, Interleukin-8B--metabolism<br/>Structure-Activity Relationship