TY - GEN AU - Liu,Ping AU - Lin,Linus S AU - Hamill,Terence G AU - Jewell,James P AU - Lanza,Thomas J AU - Gibson,Raymond E AU - Krause,Stephen M AU - Ryan,Christine AU - Eng,Waisi AU - Sanabria,Sandra AU - Tong,Xinchun AU - Wang,Junying AU - Levorse,Dorothy A AU - Owens,Karen A AU - Fong,Tung M AU - Shen,Chun-Pyn AU - Lao,Julie AU - Kumar,Sanjeev AU - Yin,Wenji AU - Payack,Joseph F AU - Springfield,Shawn A AU - Hargreaves,Richard AU - Burns,H Donald AU - Goulet,Mark T AU - Hagmann,William K TI - Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use SN - 0022-2623 PY - 2007///1015 KW - Amides KW - chemical synthesis KW - Animals KW - Brain KW - diagnostic imaging KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Fluorine Radioisotopes KW - Humans KW - Macaca mulatta KW - Positron-Emission Tomography KW - Pyridines KW - Radioligand Assay KW - Radiopharmaceuticals KW - Receptor, Cannabinoid, CB1 KW - agonists KW - Recombinant Proteins KW - metabolism KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm070131b ER -