TY - GEN AU - Fan,Jinshui AU - Wilson,Paul F AU - Wong,Heng-Kuan AU - Urbin,Salustra S AU - Thompson,Larry H AU - Wilson,David M TI - XRCC1 down-regulation in human cells leads to DNA-damaging agent hypersensitivity, elevated sister chromatid exchange, and reduced survival of BRCA2 mutant cells SN - 0893-6692 PY - 2007///0906 KW - Animals KW - BRCA2 Protein KW - metabolism KW - CHO Cells KW - Cell Extracts KW - Cell Survival KW - drug effects KW - Chromosomal Instability KW - Cricetinae KW - Cricetulus KW - DNA Damage KW - DNA-Binding Proteins KW - genetics KW - Down-Regulation KW - HeLa Cells KW - Humans KW - Methyl Methanesulfonate KW - toxicity KW - Micronucleus Tests KW - Mutagens KW - Mutation KW - Neoplasms KW - pathology KW - RNA, Small Interfering KW - Sister Chromatid Exchange KW - Transfection KW - X-ray Repair Cross Complementing Protein 1 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1002/em.20312 ER -