TY - GEN AU - Smith,Paul A AU - Selley,Dana E AU - Sim-Selley,Laura J AU - Welch,Sandra P TI - Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors SN - 0014-2999 PY - 2007///1025 KW - Analgesics, Non-Narcotic KW - administration & dosage KW - Analgesics, Opioid KW - Animals KW - Benzoxazines KW - pharmacology KW - Dose-Response Relationship, Drug KW - Dronabinol KW - Drug Synergism KW - Drug Therapy, Combination KW - Drug Tolerance KW - Enkephalin, Ala(2)-MePhe(4)-Gly(5)- KW - Guanosine 5'-O-(3-Thiotriphosphate) KW - metabolism KW - Injections, Intraperitoneal KW - Injections, Subcutaneous KW - Male KW - Morphine KW - Morpholines KW - Naphthalenes KW - Pain KW - Pain Measurement KW - Pain Threshold KW - drug effects KW - Periaqueductal Gray KW - Rats KW - Rats, Sprague-Dawley KW - Receptor, Cannabinoid, CB1 KW - agonists KW - Receptors, Opioid, mu KW - Spinal Cord KW - Sulfur Radioisotopes KW - Time Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.ejphar.2007.06.001 ER -