TY  - GEN
AU  - Outeiro,Tiago Fleming
AU  - Kontopoulos,Eirene
AU  - Altmann,Stephen M
AU  - Kufareva,Irina
AU  - Strathearn,Katherine E
AU  - Amore,Allison M
AU  - Volk,Catherine B
AU  - Maxwell,Michele M
AU  - Rochet,Jean-Christophe
AU  - McLean,Pamela J
AU  - Young,Anne B
AU  - Abagyan,Ruben
AU  - Feany,Mel B
AU  - Hyman,Bradley T
AU  - Kazantsev,Aleksey G
TI  - Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
SN  - 1095-9203
PY  - 2007///0813
KW  - Acetylation
KW  - Animals
KW  - Animals, Genetically Modified
KW  - Cell Death
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cells, Cultured
KW  - Disease Models, Animal
KW  - Dopamine
KW  - physiology
KW  - Dose-Response Relationship, Drug
KW  - Drosophila melanogaster
KW  - Furans
KW  - pharmacology
KW  - Humans
KW  - Models, Molecular
KW  - Neurons
KW  - cytology
KW  - Parkinson Disease
KW  - drug therapy
KW  - Protein Conformation
KW  - Quinolines
KW  - RNA, Small Interfering
KW  - genetics
KW  - Rats
KW  - Sirtuin 1
KW  - Sirtuin 2
KW  - Sirtuins
KW  - antagonists & inhibitors
KW  - Transfection
KW  - Tubulin
KW  - metabolism
KW  - alpha-Synuclein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/science.1143780
ER  -