TY - GEN AU - Davis,Ian D AU - Skrumsager,Birte K AU - Cebon,Jonathan AU - Nicholaou,Theo AU - Barlow,John W AU - Moller,Niels Peter Hundahl AU - Skak,Kresten AU - Lundsgaard,Dorthe AU - Frederiksen,Klaus Stensgaard AU - Thygesen,Peter AU - McArthur,Grant A TI - An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma SN - 1078-0432 PY - 2007///1004 KW - Adult KW - Aged KW - Antineoplastic Agents KW - administration & dosage KW - Dose-Response Relationship, Drug KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Granzymes KW - drug effects KW - Humans KW - Interleukin-2 Receptor alpha Subunit KW - blood KW - Interleukins KW - Male KW - Maximum Tolerated Dose KW - Melanoma KW - drug therapy KW - Middle Aged KW - Perforin KW - Pore Forming Cytotoxic Proteins KW - Recombinant Proteins KW - Interleukin-21 N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-07-0410 ER -