TY - GEN AU - Peters,Frank T AU - Dragan,Calin-A AU - Wilde,Désirée R AU - Meyer,Markus R AU - Zapp,Josef AU - Bureik,Matthias AU - Maurer,Hans H TI - Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinobutyrophenone SN - 0006-2952 PY - 2007///0921 KW - Biotechnology KW - Butyrophenones KW - metabolism KW - Chromatography, High Pressure Liquid KW - Cytochrome P-450 CYP2D6 KW - genetics KW - Gas Chromatography-Mass Spectrometry KW - Humans KW - Magnetic Resonance Spectroscopy KW - Pyrrolidines KW - Recombinant Proteins KW - Schizosaccharomyces KW - Spectrophotometry, Ultraviolet N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bcp.2007.05.010 ER -