TY  - GEN
AU  - Cai,Shi-Ying
AU  - Xiong,Liangshi
AU  - Wray,Charles G
AU  - Ballatori,Nazzareno
AU  - Boyer,James L
TI  - The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution
SN  - 0363-6119
PY  - 2007///1017
KW  - Animals
KW  - Bile Acids and Salts
KW  - pharmacology
KW  - Biological Evolution
KW  - Cloning, Molecular
KW  - DNA
KW  - genetics
KW  - DNA-Binding Proteins
KW  - drug effects
KW  - Electrophoretic Mobility Shift Assay
KW  - Genes, Reporter
KW  - Glutathione Transferase
KW  - metabolism
KW  - Humans
KW  - Lanosterol
KW  - Ligands
KW  - Luciferases
KW  - Models, Molecular
KW  - Phylogeny
KW  - Plasmids
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Skates, Fish
KW  - physiology
KW  - Substrate Specificity
KW  - Tissue Distribution
KW  - Transcription Factors
KW  - Tretinoin
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1152/ajpregu.00781.2006
ER  -