Cai, Shi-Ying <br/><br/>
The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution.  [electronic resource] 

 -  American journal of physiology. Regulatory, integrative and comparative physiology  Sep 2007 
 - R1400-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>0363-6119 
<br/><br/><label>Standard No.: </label>10.1152/ajpregu.00781.2006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Bile Acids and Salts--pharmacology<br/>Biological Evolution<br/>Cloning, Molecular<br/>DNA--genetics<br/>DNA-Binding Proteins--drug effects<br/>Electrophoretic Mobility Shift Assay<br/>Genes, Reporter--genetics<br/>Glutathione Transferase--metabolism<br/>Humans<br/>Lanosterol--pharmacology<br/>Ligands<br/>Luciferases--genetics<br/>Models, Molecular<br/>Phylogeny<br/>Plasmids--genetics<br/>Receptors, Cytoplasmic and Nuclear--drug effects<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Skates, Fish--physiology<br/>Substrate Specificity<br/>Tissue Distribution<br/>Transcription Factors--drug effects<br/>Tretinoin--pharmacology