Jay, Steven M <br/><br/>
Foreign body giant cell formation is preceded by lamellipodia formation and can be attenuated by inhibition of Rac1 activation.  [electronic resource] 

 -  The American journal of pathology  Aug 2007 
 - 632-40 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>0002-9440 
<br/><br/><label>Standard No.: </label>10.2353/ajpath.2007.061213  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoquinolines--pharmacokinetics<br/>Animals<br/>Bone Marrow Cells--drug effects<br/>Cell Shape--drug effects<br/>Chemokine CCL2--genetics<br/>Dose-Response Relationship, Drug<br/>Drug Implants<br/>Genotype<br/>Giant Cells, Foreign-Body--drug effects<br/>Granulocyte-Macrophage Colony-Stimulating Factor--pharmacology<br/>Interleukin-4--pharmacology<br/>Macrophages--drug effects<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Microspheres<br/>Monomeric GTP-Binding Proteins--antagonists & inhibitors<br/>Phagocytosis--drug effects<br/>Pseudopodia--metabolism<br/>Pyrimidines--pharmacokinetics<br/>RNA Interference<br/>RNA, Small Interfering--genetics<br/>rac1 GTP-Binding Protein--antagonists & inhibitors