TY - GEN AU - Johnson,Christopher M AU - Lyle,Elizabeth A AU - Omueti,Katherine O AU - Stepensky,Vitaly A AU - Yegin,Olcay AU - Alpsoy,Erkan AU - Hamann,Lutz AU - Schumann,Ralf R AU - Tapping,Richard I TI - Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy SN - 0022-1767 PY - 2007///0801 KW - Alleles KW - Amino Acid Substitution KW - Cell Membrane KW - chemistry KW - Cells, Cultured KW - Gene Frequency KW - Homozygote KW - Humans KW - Isoleucine KW - Leprosy KW - genetics KW - Monocytes KW - immunology KW - Mycobacterium leprae KW - Polymorphism, Single Nucleotide KW - Protein Transport KW - Serine KW - Toll-Like Receptor 1 KW - analysis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.178.12.7520 ER -