TY  - GEN
AU  - Pei,Xin-Yan
AU  - Dai,Yun
AU  - Tenorio,Sarah
AU  - Lu,Jianghua
AU  - Harada,Hisashi
AU  - Dent,Paul
AU  - Grant,Steven
TI  - MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism
SN  - 0006-4971
PY  - 2007///1030
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - antagonists & inhibitors
KW  - Bcl-2-Like Protein 11
KW  - Benzamides
KW  - Blotting, Western
KW  - Drug Synergism
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Immunoprecipitation
KW  - Insulin-Like Growth Factor I
KW  - Interleukin-6
KW  - MAP Kinase Kinase 1
KW  - MAP Kinase Kinase 2
KW  - Membrane Proteins
KW  - Multiple Myeloma
KW  - drug therapy
KW  - Phosphorylation
KW  - Protein Conformation
KW  - Protein Kinase C
KW  - Protein Transport
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - metabolism
KW  - RNA, Small Interfering
KW  - Staurosporine
KW  - analogs & derivatives
KW  - Subcellular Fractions
KW  - bcl-2 Homologous Antagonist-Killer Protein
KW  - bcl-2-Associated X Protein
KW  - bcl-X Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1182/blood-2007-04-083204
ER  -