Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy. [electronic resource]
- The Journal of clinical investigation Nov 1990
- 1480-8 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI114865 doi
2-Chloroadenosine--analogs & derivatives Adenosine Triphosphate--metabolism Cell Survival--drug effects Cells, Cultured Cladribine DNA Damage Deoxyadenosines--pharmacology Humans Interleukin-6--metabolism Lymphoma, T-Cell--blood Monocytes--cytology Mutagens NAD--metabolism Phagocytosis--drug effects Protein Biosynthesis RNA--biosynthesis Time Factors