TY - GEN AU - Koga,Fumitaka AU - Tsutsumi,Shinji AU - Neckers,Leonard M TI - Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells SN - 1551-4005 PY - 2007///0809 KW - Antibiotics, Antineoplastic KW - pharmacology KW - Benzoquinones KW - Breast Neoplasms KW - pathology KW - Carcinoma KW - Cell Hypoxia KW - Cell Line, Tumor KW - drug effects KW - Cobalt KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Drug Screening Assays, Antitumor KW - Extracellular Matrix Proteins KW - metabolism KW - Feedback, Physiological KW - Female KW - Fibronectins KW - Focal Adhesions KW - Gene Expression Regulation, Neoplastic KW - HSP90 Heat-Shock Proteins KW - antagonists & inhibitors KW - Hepatocyte Growth Factor KW - Humans KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - biosynthesis KW - Integrin beta3 KW - genetics KW - Lactams, Macrocyclic KW - Neoplasm Invasiveness KW - Neoplasm Proteins KW - Neovascularization, Pathologic KW - drug therapy KW - Proto-Oncogene Proteins c-met KW - Stress Fibers KW - Urinary Bladder Neoplasms KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4161/cc.6.11.4296 ER -