Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity. [electronic resource]
- The American journal of pathology Jun 2007
- 1917-30 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
0002-9440
10.2353/ajpath.2007.060993 doi
Adolescent Adult Animals Antibiotics, Antineoplastic--therapeutic use Apoptosis--physiology Bone Neoplasms--drug therapy Caspase 8--genetics Cell Line Child Doxorubicin--therapeutic use Drug Resistance, Neoplasm Embryonic Stem Cells--cytology Female Humans Interferon-gamma--metabolism Male Sarcoma, Ewing--drug therapy Survival Rate TNF-Related Apoptosis-Inducing Ligand--metabolism Up-Regulation