Louie, Arnold

Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. [electronic resource] - Antimicrobial agents and chemotherapy Aug 2007 - 2661-7 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0066-4804

10.1128/AAC.00073-07 doi


Animals
Anti-Bacterial Agents--pharmacokinetics
Colony Count, Microbial
Disease Models, Animal
Drug Resistance, Bacterial--genetics
Humans
Immunocompetence
Levofloxacin
Mice
Microbial Sensitivity Tests--methods
Mutation
Neutropenia
Ofloxacin--pharmacokinetics
Plague--drug therapy
Selection, Genetic
Streptomycin--pharmacokinetics
Thigh--microbiology
Treatment Outcome
Yersinia pestis--drug effects