Zhang, Jiange <br/><br/>
Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jul 2007 
 - 3769-73 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2007.04.010  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anticonvulsants--chemistry<br/>Carboxylic Acids--chemical synthesis<br/>Chemistry, Pharmaceutical--methods<br/>Drug Design<br/>GABA Antagonists--chemical synthesis<br/>GABA Plasma Membrane Transport Proteins--chemistry<br/>Imidazoles--chemistry<br/>Inhibitory Concentration 50<br/>Mice<br/>Models, Chemical<br/>Nipecotic Acids--chemistry<br/>Piperidines--chemical synthesis<br/>Structure-Activity Relationship<br/>Temperature<br/>Tiagabine<br/>gamma-Aminobutyric Acid--pharmacokinetics