TY  - GEN
AU  - Choi,Hoo-Kyun
AU  - Chun,Myung-Kwan
AU  - Lee,Se Hee
AU  - Jang,Mee Hee
AU  - Kim,Hee Doo
AU  - Jung,Chun Sik
AU  - Oh,Seaung Youl
TI  - In vitro and in vivo study of poly(ethylene glycol) conjugated ketoprofen to extend the duration of action
SN  - 0378-5173
PY  - 2007///0921
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - administration & dosage
KW  - Carrageenan
KW  - Chemistry, Pharmaceutical
KW  - Delayed-Action Preparations
KW  - Dicyclohexylcarbodiimide
KW  - chemistry
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Drug Carriers
KW  - Drug Compounding
KW  - Hydrogen-Ion Concentration
KW  - Hydrolysis
KW  - Inflammation
KW  - chemically induced
KW  - Injections, Intramuscular
KW  - Injections, Intravenous
KW  - Ketoprofen
KW  - Magnetic Resonance Spectroscopy
KW  - Male
KW  - Molecular Weight
KW  - Pain Measurement
KW  - Pain Threshold
KW  - drug effects
KW  - Polyethylene Glycols
KW  - Prodrugs
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Solubility
KW  - Spectroscopy, Fourier Transform Infrared
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ijpharm.2007.03.045
ER  -