Koukos, Georgios

Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT. [electronic resource] - The Biochemical journal Aug 2007 - 167-74 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20070296 doi


ATP Binding Cassette Transporter 1
ATP-Binding Cassette Transporters--metabolism
Adenoviridae
Animals
Apolipoprotein A-I--blood
Biological Transport
Cell Line
Cholesterol--metabolism
Chromatography, Liquid
Enzyme Activation
Gene Expression Regulation
Genetic Therapy
Humans
Lipids--blood
Lipoproteins--chemistry
Lipoproteins, HDL--chemistry
Liver--metabolism
Mice
Mutant Proteins--metabolism
Mutation--genetics
Phenotype
Phosphatidylcholine-Sterol O-Acyltransferase--genetics