TY  - GEN
AU  - Yang,Jing
AU  - Ikezoe,Takayuki
AU  - Nishioka,Chie
AU  - Tasaka,Taizo
AU  - Taniguchi,Ayuko
AU  - Kuwayama,Yoshio
AU  - Komatsu,Naoki
AU  - Bandobashi,Kentaro
AU  - Togitani,Kazuto
AU  - Koeffler,H Phillip
AU  - Taguchi,Hirokuni
AU  - Yokoyama,Akihito
TI  - AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo
SN  - 0006-4971
PY  - 2007///1030
KW  - Animals
KW  - Antibiotics, Antineoplastic
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Aurora Kinase A
KW  - Aurora Kinase B
KW  - Aurora Kinases
KW  - Case-Control Studies
KW  - Cell Cycle
KW  - Cell Proliferation
KW  - Colony-Forming Units Assay
KW  - Daunorubicin
KW  - Drug Synergism
KW  - Drug Therapy, Combination
KW  - Drug Tolerance
KW  - Enzyme Inhibitors
KW  - Female
KW  - Flow Cytometry
KW  - Humans
KW  - Immunoblotting
KW  - Leukemia
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Organophosphates
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Quinazolines
KW  - Thymidine
KW  - metabolism
KW  - Transplantation, Heterologous
KW  - Tubulin Modulators
KW  - Vincristine
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood-2007-02-073700
ER  -