TY - GEN AU - Olafsen,Tove AU - Kenanova,Vania E AU - Wu,Anna M TI - Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment SN - 1750-2799 PY - 2007///1030 KW - Animals KW - Antibodies KW - genetics KW - Half-Life KW - Isotope Labeling KW - methods KW - Mutagenesis, Site-Directed KW - Receptors, Fc KW - metabolism KW - Recombinant Proteins KW - isolation & purification N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/nprot.2006.322 ER -