TY  - GEN
AU  - Venkatesh,Pilla Reddy
AU  - Goh,Evelyn
AU  - Zeng,Peizi
AU  - New,Lee Sun
AU  - Xin,Liu
AU  - Pasha,Mohammed Khalid
AU  - Sangthongpitag,Kanda
AU  - Yeo,Pauline
AU  - Kantharaj,Ethirajulu
TI  - In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species
SN  - 0918-6158
PY  - 2007///0627
KW  - Administration, Oral
KW  - Animals
KW  - Benzimidazoles
KW  - blood
KW  - Biological Availability
KW  - Caco-2 Cells
KW  - Cell Membrane Permeability
KW  - drug effects
KW  - Cytochrome P-450 Enzyme System
KW  - metabolism
KW  - Dogs
KW  - Drug Evaluation, Preclinical
KW  - Enzyme Inhibitors
KW  - Female
KW  - Half-Life
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Hydroxamic Acids
KW  - Male
KW  - Metabolic Detoxication, Phase I
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Microsomes, Liver
KW  - Pyrroles
KW  - Pyrrolidines
KW  - Rats
KW  - Rats, Wistar
KW  - Vorinostat
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1248/bpb.30.1021
ER  -