Venkatesh, Pilla Reddy <br/><br/>
In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species.  [electronic resource] 

 -  Biological & pharmaceutical bulletin  May 2007 
 - 1021-4 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0918-6158 
<br/><br/><label>Standard No.: </label>10.1248/bpb.30.1021  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Benzimidazoles--blood<br/>Biological Availability<br/>Caco-2 Cells<br/>Cell Membrane Permeability--drug effects<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Dogs<br/>Drug Evaluation, Preclinical<br/>Enzyme Inhibitors--blood<br/>Female<br/>Half-Life<br/>Histone Deacetylase Inhibitors<br/>Humans<br/>Hydroxamic Acids--blood<br/>Male<br/>Metabolic Detoxication, Phase I<br/>Mice<br/>Mice, Inbred BALB C<br/>Microsomes, Liver--drug effects<br/>Pyrroles--blood<br/>Pyrrolidines<br/>Rats<br/>Rats, Wistar<br/>Vorinostat