TY - GEN AU - Zhang,Fang AU - Thornhill,Susannah I AU - Howe,Steven J AU - Ulaganathan,Meera AU - Schambach,Axel AU - Sinclair,Joanna AU - Kinnon,Christine AU - Gaspar,H Bobby AU - Antoniou,Michael AU - Thrasher,Adrian J TI - Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells SN - 0006-4971 PY - 2007///1019 KW - Animals KW - Chromatin KW - genetics KW - Chromosomal Proteins, Non-Histone KW - Cytomegalovirus KW - Disease Models, Animal KW - Enhancer Elements, Genetic KW - Gene Expression KW - Gene Silencing KW - Genetic Therapy KW - Genetic Vectors KW - Genome, Viral KW - HeLa Cells KW - Hematopoietic Stem Cells KW - Heterogeneous-Nuclear Ribonucleoprotein Group A-B KW - Humans KW - Interleukin-2 KW - K562 Cells KW - Lentivirus KW - Mice KW - Mice, SCID KW - Promoter Regions, Genetic KW - Signal Transduction KW - Spleen Focus-Forming Viruses KW - Transduction, Genetic KW - Transgenes KW - physiology KW - Virus Integration KW - X-Linked Combined Immunodeficiency Diseases N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2006-12-060814 ER -