TY - GEN AU - Kunnumakkara,Ajaikumar B AU - Guha,Sushovan AU - Krishnan,Sunil AU - Diagaradjane,Parmeswaran AU - Gelovani,Juri AU - Aggarwal,Bharat B TI - Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products SN - 0008-5472 PY - 2007///0523 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Apoptosis KW - drug effects KW - Cell Growth Processes KW - Cell Line, Tumor KW - Curcumin KW - administration & dosage KW - Cyclooxygenase 2 KW - biosynthesis KW - Deoxycytidine KW - Down-Regulation KW - Drug Synergism KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Male KW - Matrix Metalloproteinase 9 KW - Mice KW - NF-kappa B KW - antagonists & inhibitors KW - Neovascularization, Pathologic KW - drug therapy KW - Pancreatic Neoplasms KW - blood supply KW - Vascular Endothelial Growth Factor A KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-06-4257 ER -