TY - GEN AU - Lim,Yun-Ping AU - Huang,Jin-Ding TI - Pregnane X receptor polymorphism affects CYP3A4 induction via a ligand-dependent interaction with steroid receptor coactivator-1 SN - 1744-6872 PY - 2007///0529 KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Cell Line, Tumor KW - Chromatography, Affinity KW - Clotrimazole KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme System KW - metabolism KW - Electrophoretic Mobility Shift Assay KW - Enzyme Inhibitors KW - Growth Inhibitors KW - Histone Acetyltransferases KW - Humans KW - Immunoprecipitation KW - Ligands KW - Mutagenesis, Site-Directed KW - Mutation KW - genetics KW - Nuclear Receptor Coactivator 1 KW - Paclitaxel KW - Plasmids KW - Polymorphism, Genetic KW - Pregnane X Receptor KW - Receptors, Steroid KW - Rifampin KW - Transcription Factors KW - Transcriptional Activation KW - Two-Hybrid System Techniques N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1097/FPC.0b013e32803e40d7 ER -