TY - GEN AU - Nishikimi,Toshio AU - Koshikawa,Shogo AU - Ishikawa,Yayoi AU - Akimoto,Kazumi AU - Inaba,Chikako AU - Ishimura,Kimihiko AU - Ono,Hidehiko AU - Matsuoka,Hiroaki TI - Inhibition of Rho-kinase attenuates nephrosclerosis and improves survival in salt-loaded spontaneously hypertensive stroke-prone rats SN - 0263-6352 PY - 2007///0625 KW - 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine KW - analogs & derivatives KW - Animals KW - Collagen Type I KW - metabolism KW - Collagen Type III KW - Gene Expression KW - Immunohistochemistry KW - Intercellular Adhesion Molecule-1 KW - Intracellular Signaling Peptides and Proteins KW - antagonists & inhibitors KW - Kidney KW - drug effects KW - Kidney Function Tests KW - Male KW - NADP KW - Nephrosclerosis KW - drug therapy KW - Plasminogen Activator Inhibitor 1 KW - Protein Kinase Inhibitors KW - pharmacology KW - Protein Serine-Threonine Kinases KW - Rats KW - Rats, Inbred SHR KW - Rats, Inbred WKY KW - Sodium Chloride, Dietary KW - adverse effects KW - Transforming Growth Factor beta KW - rho GTP-Binding Proteins KW - rho-Associated Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1097/HJH.0b013e3280825440 ER -