TY  - GEN
AU  - Joseph,Jeremiah S
AU  - Saikatendu,Kumar Singh
AU  - Subramanian,Vanitha
AU  - Neuman,Benjamin W
AU  - Buchmeier,Michael J
AU  - Stevens,Raymond C
AU  - Kuhn,Peter
TI  - Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch
SN  - 0022-538X
PY  - 2007///0711
KW  - Allosteric Site
KW  - Animals
KW  - Binding Sites
KW  - Catalytic Domain
KW  - Cloning, Molecular
KW  - Crystallography, X-Ray
KW  - Dimerization
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Endoribonucleases
KW  - Manganese
KW  - chemistry
KW  - Molecular Conformation
KW  - Mutagenesis
KW  - Protein Conformation
KW  - RNA-Dependent RNA Polymerase
KW  - Severe acute respiratory syndrome-related coronavirus
KW  - enzymology
KW  - Viral Nonstructural Proteins
KW  - Xenopus laevis
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1128/JVI.02817-06
ER  -